Jessica O. Winter, Ph.D.
Assistant Professor
Education and experience
B.S., Northwestern University, 1997
Intel Corporation 1997-1999
M.S., University of Texas at Austin, 2001
Ph.D., University of Texas at Austin, 2004
Postdoctoral Fellow, Boston VA Hospital, 2004-2006
Contact Information
Department of Chemical and Biomolecular Engineering
Department of Biomedical Engineering
The Ohio State University
335 Koffolt Laboratories
140 West 19th Ave.
Columbus, OH 43210
Phone: (614) 247-7668
Fax: (614) 292-3769
Email: winter.63@osu.edu
Honors
NSF Graduate Research Fellow 2001-2004
MRS Graduate Student Gold Award 2003
BMES Graduate Student Award 2003
Research Activities and Interests
Nanobiotechnology, Cell and Tissue Engineering, Neural Prosthetics. Specifically:
Nanoscale Neural Prosthetics: The first area focuses on the development of nanocomponents to directly manipulate the contents of nerve cells. Initial work in this area examines the selective binding of nanoparticles to subcellular structures (i.e., ion channels, neurotransmitters, and chemical-containing vesicles). Delivery and targeting methods are explored using techniques developed for gene therapy.
Patterning for Neural Adhesion and Synapse Formation: I am investigating the effects of nano-patterned physical and chemical cues on neuron-neuron and neuron-electrode interactions. I am interested in patterns which enhance physical and electrical interfaces among nerve cells and underlying electronic devices. This technology has the potential to greatly increase the sensitivity of neural recording devices, biosensors, and prosthetics.
Bio-Inspired Surfaces: Nature has created several elegant schemes to organize elements at the nanoscale: Protein folding, DNA replication, and transport along microtubules all occur with remarkable fidelity. I am exploiting some of these methods to create "bio-inspired" surfaces. These surfaces use biomolecules to assemble and manipulate nanoparticles into coherent structures. These structures may serve as tissue engineering substrates, biomaterial coatings, or as elements of electronic devices.
Selected Publications
- J.O. Winter, S. Cogan, J.F. Rizzo, III (2005). "Visual Prostheses: Current Challenges and Future Outlook" In Preparation.
- N. Gomez, J.O. Winter, F. Shieh, A.E. Saunders, B.A. Korgel, C.E. Schmidt (2005). Challenges in Quantum Dot-Neuron Active Interfacing. Talanta 67(3):462-471.
- J. O. Winter, N. Gomez, B. A. Korgel, C. E. Schmidt (2005). "Quantum Dots for Electrical Stimulation of Neural Cells," Proceedings of SPIE: Nanobiophotonics and Biomedical Applications II. Alexander N. Cartwright, Marek Osinski, Eds. 5705: 235-246.
- J.O. Winter, S. Gatzert, B.A. Korgel, C.E. Schmidt (2005). "Variation of Cadmium Sulfide Nanoparticles Size with Altered Aqueous Synthesis Conditions." Colloids and Surfaces A, 254(1-3): 147-157.
